Batman: the Brave and the Bold Wiki
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For all of OMAC's efforts, the Great Disaster could not be averted. Very little is known as to the true causes of the Disaster, but what scant evidence exists points towards a mysterious energy wall known only as the Vortex. Earthquakes and tidal waves erupted all across the globe and the nations of Earth found themselves at the mercy of nuclear Armageddon. Shortly before the final bastions of humanity were to fall, a scientist named Doctor Michael Grant invented a mutagenic chemical known as Cortexin. Although he would not survive long enough to witness the fruits of his labor, the Cortexin drug would succeed in carving out its own legacy in the wake of global annihilation. Following the Great Disaster, Buddy Blank found himself cut off from the satellite Brother-Eye. He retired as OMAC and set out to eke a new life for himself as ordinary Buddy Blank in this new post-apocalyptic era.

The ambient radiation left behind by the Great Disaster interacted with the Cortexin levels in many of Dr. Grant's laboratory test animals. Over the course of two generations, the animals began to mutate, and their progeny eventually developed anthropomorphic traits including human intellect and the ability to walk upright. With time, these Animal Men inherited the Earth and became the planet's dominant life form. Humanity was left devoid of all culture and social structure, and slowly began to de-evolve into a lesser species (Whether the Cortexin Effect had anything to do with this process is unknown).

The Last Boy on Earth Decades later, the aging Buddy Blank returned to an army compound located in the ruins of New York City named Command-D. By this time period, the tribes of the Tiger-Men under the Great Caesar had erected the Tiger Empire. Their domain covered most of the Eastern seaboard of the United States. Buddy was careful to conceal himself or else risk becoming prey to the Empire's anti-human initiatives. Buddy sired a child who in turn later gave birth to a son named Kamandi . Kamandi's name was derived from the bunker in which he had been born (Command-D).

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